茆广华：博士，副教授，硕士生导师
邮箱：maoyun82@sina.com
简况：
茆广华，女，1982年1月生，江苏盐城人，工学博士。2014年6月毕业于江苏大学食品与生物工程学院 食品科学专业，获工学博士学位；同年6月进入必赢766net手机版工作。
研究领域：
环境污染与健康效应、天然产物的资源化利用等。
承担课题：
1. 环境化学与生态毒理学国家重点实验室开放基金，KF2020-11，十溴联苯醚母体暴露致幼年期子代大鼠的免疫毒性效应及分子机制研究，2020/08-2022/07, 4.25万元，主持，在研。
2. 江苏大学应急管理学院专项科研项目，KY-C-10，入太湖丹金溧漕河（丹阳段）及沿线水体中新烟碱类杀虫 剂的污染特征、生态风险及生物毒性研究，2022.1-2024.12，2万元，主持，在研。
3. 江苏省自然科学青年基金，BK20160497，持久性有机污染物十溴联苯醚致老年期小鼠免疫毒性易感性及分子机制，2016/07-2019/06, 20万元，主持，结题。
4. 江苏省高校自然科学面上项目，16KJB610005，BDE209致老年期小鼠免疫毒性易感性及其分子机制，2016/09-2018/08, 5万元，主持，结题。
5. 浙江省科技厅公益技术农业项目，2012C2008，富硒灰树花栽培及综合利用研究，2012/01-2014/01, 20万元，主持，结题。
6. 国家富民强县项目子项目，2012-44，多糖终端产品产业化开发，2013/01-2014/12，20万元，主持，结题。
7. 浙江省科技厅高技能人才培养和技术创新活动资助项目，2009R30039，灰树花多糖D组分纯化工艺的研发，2009/02-2010/12, 5万元，主持，结题。
8. 国家自然科学基金面上项目，31471580，灰树花硒多糖的吸收变化及其参与免疫调节的分子机制研究，2015/01-2018/12，87万，参与，结题。
9. 浙江省科技厅重大科技专项重点农业项目，香菇、灰树花、银耳加工关键技术与新产品开发，2008/07-2011/06, 80 万元，参与，结题。
科研论文：
[1] Yangyang Ding, Yao Chen, Weiwei Feng, Guijuan Huang, Mingyue Dong, Ting Zhao, Na Chen, Liuqing Yang, Guanghua Mao*, Xiangyang Wu. Persistent immune injury induced by short-term decabromodiphenyl ether (BDE-209) exposure to female middle-aged Balb/c mice. Environmental Science and Pollution Research, 2023, DOI10.1007/s11356-023-30148
[2] Guanghua Mao*, Junjie Tang, Taotao Liao, Xiaoxiang Shi, FangYuan Dong, Weiwei Feng, Yao Chen, Ting Zhao, Xiangyang Wu, Liuqing Yang. Metabolism toxicity and susceptibility of decabromodiphenyl ether (BDE-209) exposure on BRL cells with insulin resistance. Environmental Science and Pollution Research, 2023, 29(60), 91306-91324.
[3] Guanghua Mao, Ping Yu, Ting Zhao, Yao Chen, Weiwei Feng, Qiaoyue Zhang, Liuqing Yang*, Xiangyang Wu*. Aqueous two-phase simultaneous extraction and purification of a polysaccharide from Grifola frondosa: Process optimization, structural characteristics and antioxidant activity. Industrial Crops and Products, 2022,184, 114962
[4] Zhehan Zhang, Taotao Liao, Chunmeng Deng, Baorui Li, Emmanuel Sunday Okeke, Weiwei Feng, Yao Chen, Ting Zhao, Guanghua Mao*, Xiangyang Wu*. Purification and characterization of Se-enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+-induced immune toxicity. Journal of the science of food and agriculture, 2022,102(6), 2526-2537.
[5] Taotao Liao, Baorui Li, Zhehan Zhang, Weiwei Feng, Yao Chen, Ting Zhao, Guanghua Mao*, Xiangyang Wu*. Short-term exposure of decabromodiphenyl ether in female adult Balb/c mice: Immune toxicity and self-recovery. Toxicology letters, 2021,342, 26-37.
[6] Guanghua Mao, Hongyang Liu, Yangyang Ding, Weijie Zhang, Hui Chen, Ting Zhao, Weiwei Feng, Xiangyang Wu*, Liuqing Yang*. Evaluation of combined developmental neurological toxicity of di (n-butyl) phthalates and lead using immature mice. Environmental Science and Pollution Research, 2020, 27(9), 9318-9326.
[7] Guanghua Mao, Zhehan Zhang, Fan Fei, Yangyang Ding, Weijie Zhang, Hui Chen, Sameh Samir Ali, Ting Zhao, Weiwei Feng, Xiangyang Wu*, Liuqing Yang*. Effect of Grifola frondosa polysaccharide on anti-tumor activity in combination with 5-Fu in Heps-bearing mice. International Journal of Biological Macromolecules. 2019, 121:930-935
[8] Guanghua Mao, Qian Li, Chunmeng Deng, Yaqian Wang, Yangyang Ding, Weijie Zhang, Yao Chen, Ting Zhao, Weiwei Feng, Liuqing Yang*, Xiangyang Wu*. The synergism and attenuation effect of Selenium (Se)-enriched Grifola frondosa (Se)-polysaccharide on 5-Fluorouracil (5-Fu) in Heps-bearing mice. International Journal of Biological Macromolecules. 2018, 107(Pt B):2211-2216
[9] Guanghua Mao, Zhaoxiang Zhou, Yao Chen, Wei Wang, Xueshan Wu, Weiwei Feng, Samuel Jerry Cobbina, Jing Huang, Zhen Zhang, Hai Xu，Liuqing Yang*, Xiangyang Wu*. Neurological Toxicity of Individual and Mixtures of Low Dose Arsenic, Mono and Di (n-butyl) Phthalates on Sub-Chronic Exposure to Mice. Biological Trace Element Research. 2016, 170 (1): 183-193
[10] Guanghua Mao, Yi Ren, Qian Li, Huiyu Wu, Dun Jin, Ting Zhao, Caiquan Xu, Denghong Zhang, Qingdong Jia, Yanpeng Bai , Liuqing Yang*, Xiangyang Wu*. Anti-tumor and immunomodulatory activity of selenium (Se)-polysaccharide from Se-enriched Grifola frondosa. International Journal of Biological Macromolecules. 2016, 82:607-613
[11] Guanghua Mao, Yi Ren, Weiwei Feng, Qian Li, Huiyu Wu, Dun jin, Ting Zhao, Caiquan Xu, Liuqing Yang*, and Xiangyang Wu*. Antitumor and immunomodulatory activity of a water-soluble polysaccharide from Grifola frondosa. Carbohydrate Polymers. 2015,134:406-412
[12] Guanghua Mao, Ye Zou, Weiwei Feng, Wei Wang, Ting Zhao, Changwen Ye, Yang Zhu, Xueshan Wu, liuqing Yang*, Xiangyang Wu*. Extraction, preliminary characterization and antioxidant activity of Se-enriched Maitake polysaccharide. Carbohydrate Polymers. 2014, 101(1): 213-219
[13] Guanghua Mao, Weiwei Feng, Hui Xiao, Ting Zhao, Fang Li, Ye Zou, Yuena Ren, Yang Zhu, Liuqing Yang*, Xiangyang Wu*. Purification, Characterization, and Antioxidant Activities of Selenium-Containing Protein and Polysaccharide in Royal Sun Mushroom, Agaricus brasiliensis (Higher Basidiomycetes). International Journal of Mushrooms. 2014, 16(5):463-476
获奖情况：
第八届全国大学生生命科学竞赛（创新创业类），三等奖两项，第二指导教师；
2013 年获浙江省“151人才工程”，丽水市“138 人才工程”；
2012年获丽水市科学技术进步二等奖一项（排名第二）。
